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Hypersomnia During Cancer Treatment

What is hypersomnia?

A good night's sleep is important for your functioning and well-being. But too much sleep can also be a problem. One side effect of cancer and cancer treatment is sleeping too much. This is called hypersomnia. Hypersomnia that's linked to chemotherapy treatment often improves after treatment ends.

Hypersomnia is different from fatigue. Fatigue is the feeling of being tired, but able to stay awake if you try. If you have hypersomnia, you have trouble staying awake when you want to and try to. You may sleep 10 hours at night, but still have trouble staying awake during the day. This sleep problem can be caused by cancer treatments or other medicines.

Causes of hypersomnia

Cancer-related hypersomnia may be caused by:

  • Low levels of red blood cells (anemia)

  • Depression

  • Anxiety

  • Pain

  • Hormone changes, such as hypothyroidism

  • Certain prescription or over-the-counter medicines. These include chemotherapy, antinausea medicine, sedatives, antihistamines, pain medicines, and antidepressants.

Symptoms of hypersomnia

You may have hypersomnia if you have these symptoms for 3 weeks or more:

  • 10 hours or more of sleep at night

  • Trouble staying awake during the day despite a full night’s sleep

Managing hypersomnia

The treatment for cancer-related hypersomnia depends on the cause. If your sleep problem is due to your treatment, your healthcare provider may want to prescribe medicine to help you stay awake. If your sleep problem is due to depression or stress, your provider may prescribe medicine or refer you to a counselor or therapist.

These tips may help you manage hypersomnia: 

  • Exercise daily in the morning or early afternoon instead of near bedtime.

  • Keep a regular sleep schedule, with the same wake-up and bedtime every day.

  • Do things you enjoy that need your full attention.

  • Don't eat heavy meals or foods that make you sleepy during the day.

  • Don't have alcohol or caffeine.

Online Medical Reviewer: Jessica Gotwals RN BSN MPH
Online Medical Reviewer: Rita Sather RN
Online Medical Reviewer: Todd Gersten MD
Date Last Reviewed: 5/1/2023
© 2024 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare provider's instructions.